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Cell-Free Expression of Sodium Channel Domains for Pharmacology Studies. Noncanonical Spider Toxin Binding Site in the Second Voltage-Sensing Domain of Human Na(v)1.4 Channel

Voltage-gated sodium (Na(V)) channels are essential for the normal functioning of cardiovascular, muscular, and nervous systems. These channels have modular organization; the central pore domain allows current flow and provides ion selectivity, whereas four peripherally located voltage-sensing domai...

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Detalles Bibliográficos
Autores principales:	Myshkin, Mikhail Yu., Männikkö, Roope, Krumkacheva, Olesya A., Kulbatskii, Dmitrii S., Chugunov, Anton O., Berkut, Antonina A., Paramonov, Alexander S., Shulepko, Mikhail A., Fedin, Matvey V., Hanna, Michael G., Kullmann, Dimitri M., Bagryanskaya, Elena G., Arseniev, Alexander S., Kirpichnikov, Mikhail P., Lyukmanova, Ekaterina N., Vassilevski, Alexander A., Shenkarev, Zakhar O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737007/ https://www.ncbi.nlm.nih.gov/pubmed/31555136 http://dx.doi.org/10.3389/fphar.2019.00953

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