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NeTFactor, a framework for identifying transcriptional regulators of gene expression-based biomarkers
Biological and regulatory mechanisms underlying many multi-gene expression-based disease biomarkers are often not readily evident. We describe an innovative framework, NeTFactor, that combines network analyses with gene expression data to identify transcription factors (TFs) that significantly and m...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737052/ https://www.ncbi.nlm.nih.gov/pubmed/31506535 http://dx.doi.org/10.1038/s41598-019-49498-y |