The emerging role of IMD 0354 on bone homeostasis by suppressing osteoclastogenesis and bone resorption, but without affecting bone formation

Osteoporosis is caused by an imbalance between bone formation and bone resorption. Receptor activator of nuclear factor-κB ligand (RANKL) promotes the activity and differentiation of osteoclasts via activating the nuclear factor-κB (NF-κB) and mitogen-activated protein kinase (MAPK) signaling pathwa...

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Detalles Bibliográficos
Autores principales: Chen, Wenxiang, Xie, Ziang, Tang, Pan, Wang, Yongli, Jie, Zhiwei, Qin, An, Jiang, Xuesheng, Hu, Zhijun, Fan, Shunwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737093/
https://www.ncbi.nlm.nih.gov/pubmed/31506437
http://dx.doi.org/10.1038/s41419-019-1914-5

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