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A novel epitope-presenting thermostable scaffold for the development of highly specific insulin-like growth factor-1/2 antibodies

High sequence and structural homology between mature human insulin-like growth factors IGF-1 and IGF-2 makes serological discrimination by immunodiagnostic IGF tests a challenging task. There is an urgent need for highly specific IGF-1 and IGF-2 antibodies, yet only a short sequence element, i.e. th...

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Detalles Bibliográficos
Autores principales:	Peeß, Carmen, Scholz, Christian, Casagolda, David, Düfel, Hartmut, Gerg, Michael, Kowalewsky, Frank, Bocola, Marco, von Proff, Leopold, Goller, Sabine, Klöppel-Swarlik, Heidi, Hoppe, Alessandra, Schräml, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2019
Materias:	Protein Structure and Folding
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737233/ https://www.ncbi.nlm.nih.gov/pubmed/31337703 http://dx.doi.org/10.1074/jbc.RA119.007654

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