Cargando…

Combined analysis of keratinocyte cancers identifies novel genome-wide loci

The keratinocyte cancers (KC), basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) are the most common cancers in fair-skinned people. KC treatment represents the second highest cancer healthcare expenditure in Australia. Increasing our understanding of the genetic architecture of KC may pr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liyanage, Upekha E, Law, Matthew H, Han, Xikun, An, Jiyuan, Ong, Jue-Sheng, Gharahkhani, Puya, Gordon, Scott, Neale, Rachel E, Olsen, Catherine M, MacGregor, Stuart, Whiteman, David C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Association Studies Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737293/ https://www.ncbi.nlm.nih.gov/pubmed/31174203 http://dx.doi.org/10.1093/hmg/ddz121

Ejemplares similares

Height and overall cancer risk and mortality: evidence from a Mendelian randomisation study on 310,000 UK Biobank participants
por: Ong, Jue-Sheng, et al.
Publicado: (2018)

Effect of increased body mass index on risk of diagnosis or death from cancer
por: Gharahkhani, Puya, et al.
Publicado: (2019)

Polyunsaturated Fatty Acid Levels and the Risk of Keratinocyte Cancer: A Mendelian Randomization Analysis
por: Seviiri, Mathias, et al.
Publicado: (2021)

A multi-phenotype analysis reveals 19 susceptibility loci for basal cell carcinoma and 15 for squamous cell carcinoma
por: Seviiri, Mathias, et al.
Publicado: (2022)

Gastroesophageal reflux GWAS identifies risk loci that also associate with subsequent severe esophageal diseases
por: An, Jiyuan, et al.
Publicado: (2019)

Chronic gastroesophageal reflux disease shares genetic background with esophageal adenocarcinoma and Barrett's esophagus
por: Gharahkhani, Puya, et al.
Publicado: (2016)

Author Correction: Gastroesophageal reflux GWAS identifies risk loci that also associate with subsequent severe esophageal diseases
por: An, Jiyuan, et al.
Publicado: (2019)

Multitrait genetic association analysis identifies 50 new risk loci for gastro-oesophageal reflux, seven new loci for Barrett’s oesophagus and provides insights into clinical heterogeneity in reflux diagnosis
por: Ong, Jue-Sheng, et al.
Publicado: (2022)

Is Genetic Risk for Sleep Apnea Causally Linked With Glaucoma Susceptibility?
por: Ingold, Nathan, et al.
Publicado: (2022)

A comprehensive re-assessment of the association between vitamin D and cancer susceptibility using Mendelian randomization
por: Ong, Jue-Sheng, et al.
Publicado: (2021)

Large-scale multitrait genome-wide association analyses identify hundreds of glaucoma risk loci
por: Han, Xikun, et al.
Publicado: (2023)

Genome-wide enrichment analysis between endometriosis and obesity-related traits reveals novel susceptibility loci
por: Rahmioglu, Nilufer, et al.
Publicado: (2015)

Author Correction: Understanding the role of bitter taste perception in coffee, tea and alcohol consumption through Mendelian randomization
por: Ong, Jue-Sheng, et al.
Publicado: (2020)

Understanding the role of bitter taste perception in coffee, tea and alcohol consumption through Mendelian randomization
por: Ong, Jue-Sheng, et al.
Publicado: (2018)

Study profile: the Genetics of Glaucoma Study
por: Gharahkhani, Puya, et al.
Publicado: (2023)

Associations of keratinocyte cancers with snp variants in the sonic hedgehog pathway
por: Rodriguez-Acevedo, Astrid J., et al.
Publicado: (2022)

Genetic variants for smoking behaviour and risk of skin cancer
por: Dusingize, Jean Claude, et al.
Publicado: (2023)

Mitochondrial genome-wide analysis of nuclear DNA methylation quantitative trait loci
por: Laaksonen, Jaakko, et al.
Publicado: (2021)

Genome-wide association study of circulating interleukin 6 levels identifies novel loci
por: Ahluwalia, Tarunveer S, et al.
Publicado: (2021)

Discovery of genomic loci associated with sleep apnea risk through multi-trait GWAS analysis with snoring
por: Campos, Adrian I, et al.
Publicado: (2022)

Discovery and fine-mapping of kidney function loci in first genome-wide association study in Africans
por: Fatumo, Segun, et al.
Publicado: (2021)

Germline variants are associated with increased primary melanoma tumor thickness at diagnosis
por: Mangantig, Ernest, et al.
Publicado: (2020)

The effect of screening on melanoma incidence and biopsy rates
por: Whiteman, David C., et al.
Publicado: (2022)

Implementing MR‐PRESSO and GCTA‐GSMR for pleiotropy assessment in Mendelian randomization studies from a practitioner's perspective
por: Ong, Jue‐Sheng, et al.
Publicado: (2019)

Genome-wide association analysis of 350 000 Caucasians from the UK Biobank identifies novel loci for asthma, hay fever and eczema
por: Johansson, Åsa, et al.
Publicado: (2019)

A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis
por: Weidinger, Stephan, et al.
Publicado: (2013)

Genome-wide survey of parent-of-origin effects on DNA methylation identifies candidate imprinted loci in humans
por: Cuellar Partida, Gabriel, et al.
Publicado: (2018)

Normal-tension glaucoma is associated with cognitive impairment
por: Mullany, Sean, et al.
Publicado: (2022)

Genome-wide association study of primary tooth eruption identifies pleiotropic loci associated with height and craniofacial distances
por: Fatemifar, Ghazaleh, et al.
Publicado: (2013)

Meta-analysis of genome-wide association studies identifies 8 novel loci involved in shape variation of human head hair
por: Liu, Fan, et al.
Publicado: (2018)

Genome-wide association study identifies SNPs in the MHC class II loci that are associated with self-reported history of whooping cough
por: McMahon, George, et al.
Publicado: (2015)

A genome-wide analysis of 340 318 participants identifies four novel loci associated with the age of first spectacle wear
por: Patasova, Karina, et al.
Publicado: (2022)

Uncovering the complex relationship between balding, testosterone and skin cancers in men
por: Ong, Jue-Sheng, et al.
Publicado: (2023)

Genome-wide meta-analysis identifies BARX1 and EML4-MTA3 as new loci associated with infantile hypertrophic pyloric stenosis
por: Fadista, João, et al.
Publicado: (2019)

Genome-wide association study identifies nine novel loci for 2D:4D finger ratio, a putative retrospective biomarker of testosterone exposure in utero
por: Warrington, Nicole M, et al.
Publicado: (2018)

A genome-wide association scan (GWAS) for mean telomere length within the COGS project: identified loci show little association with hormone-related cancer risk
por: Pooley, Karen A., et al.
Publicado: (2013)

Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics
por: Beaumont, Robin N, et al.
Publicado: (2018)

Comprehensive follow-up of the first genome-wide association study of multiple sclerosis identifies KIF21B and TMEM39A as susceptibility loci
por: McCauley, Jacob L., et al.
Publicado: (2010)

Genome-wide association identifies ATOH7 as a major gene determining human optic disc size
por: Macgregor, Stuart, et al.
Publicado: (2010)

Multi-trait genome-wide association study identifies new loci associated with optic disc parameters
por: Bonnemaijer, Pieter W. M., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_aubdfi9nim3vp887si9heoqjfq