Carbon monoxide releasing molecule-A1 improves nonalcoholic steatohepatitis via Nrf2 activation mediated improvement in oxidative stress and mitochondrial function

Nuclear factor-erythroid 2 related factor 2 (Nrf2)-mediated signaling plays a central role in maintaining cellular redox homeostasis of hepatic cells. Carbon monoxide releasing molecule-A1 (CORM-A1) has been reported to stimulate up-regulation and nuclear translocation of Nrf2 in hepatocytes. Howeve...

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Detalles Bibliográficos
Autores principales: Upadhyay, Kapil K., Jadeja, Ravirajsinh N., Vyas, Hitarthi S., Pandya, Bhaumik, Joshi, Apeksha, Vohra, Aliasgar, Thounaojam, Menaka C., Martin, Pamela M., Bartoli, Manuela, Devkar, Ranjitsinh V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737302/
https://www.ncbi.nlm.nih.gov/pubmed/31514051
http://dx.doi.org/10.1016/j.redox.2019.101314

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