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Towards a standard diet-induced and biopsy-confirmed mouse model of non-alcoholic steatohepatitis: Impact of dietary fat source
BACKGROUND: The trans-fat containing AMLN (amylin liver non-alcoholic steatohepatitis, NASH) diet has been extensively validated in C57BL/6J mice with or without the Lep(ob)/Lep(ob) (ob/ob) mutation in the leptin gene for reliably inducing metabolic and liver histopathological changes recapitulating...
Autores principales: | Boland, Michelle L, Oró, Denise, Tølbøl, Kirstine S, Thrane, Sebastian T, Nielsen, Jens Christian, Cohen, Taylor S, Tabor, David E, Fernandes, Fiona, Tovchigrechko, Andrey, Veidal, Sanne S, Warrener, Paul, Sellman, Bret R, Jelsing, Jacob, Feigh, Michael, Vrang, Niels, Trevaskis, James L, Hansen, Henrik H |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737317/ https://www.ncbi.nlm.nih.gov/pubmed/31543682 http://dx.doi.org/10.3748/wjg.v25.i33.4904 |
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