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Icariin alleviates osteoarthritis by inhibiting NLRP3-mediated pyroptosis

BACKGROUND: Osteoarthritis (OA) is the common chronic degenerative joint bone disease that is mainly featured by joint stiffness and cartilage degradation. Icariin (ICA), an extract from Epimedium, has been preliminarily proven to show anti-osteoporotic and anti-inflammatory effects in OA. However,...

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Detalles Bibliográficos
Autores principales:	Zu, Yan, Mu, Yue, Li, Qiang, Zhang, Shu-Ting, Yan, Hong-Juan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737611/ https://www.ncbi.nlm.nih.gov/pubmed/31511005 http://dx.doi.org/10.1186/s13018-019-1307-6

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