Mild maternal hyperglycemia in INS(C93S) transgenic pigs causes impaired glucose tolerance and metabolic alterations in neonatal offspring

Alongside the obesity epidemic, the prevalence of maternal diabetes is rising worldwide, and adverse effects on fetal development and metabolic disturbances in the offspring's later life have been described. To clarify whether metabolic programming effects are due to mild maternal hyperglycemia...

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Detalles Bibliográficos
Autores principales: Renner, Simone, Martins, Ana Sofia, Streckel, Elisabeth, Braun-Reichhart, Christina, Backman, Mattias, Prehn, Cornelia, Klymiuk, Nikolai, Bähr, Andrea, Blutke, Andreas, Landbrecht-Schessl, Christina, Wünsch, Annegret, Kessler, Barbara, Kurome, Mayuko, Hinrichs, Arne, Koopmans, Sietse-Jan, Krebs, Stefan, Kemter, Elisabeth, Rathkolb, Birgit, Nagashima, Hiroshi, Blum, Helmut, Ritzmann, Mathias, Wanke, Rüdiger, Aigner, Bernhard, Adamski, Jerzy, Hrabě de Angelis, Martin, Wolf, Eckhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737953/
https://www.ncbi.nlm.nih.gov/pubmed/31308048
http://dx.doi.org/10.1242/dmm.039156

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