Cargando…

Discoidin domain receptor 1 deficiency in vascular smooth muscle cells leads to mislocalisation of N-cadherin contacts

N-cadherin mediates cell–cell contacts in vascular smooth muscle cells (VSMCs), and regulates VSMC behaviours including migration and proliferation. Discoidin domain receptor 1 (DDR1) is a collagen binding receptor also implicated in these processes. Previous studies have shown that both N-cadherin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Songyi, Bala, Sudarshan, Bendeck, Michelle P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737968/ https://www.ncbi.nlm.nih.gov/pubmed/31362952 http://dx.doi.org/10.1242/bio.041913

Ejemplares similares

DDR1 (Discoidin Domain Receptor-1)-RhoA (Ras Homolog Family Member A) Axis Senses Matrix Stiffness to Promote Vascular Calcification
por: Ngai, David, et al.
Publicado: (2020)

Interactions between the discoidin domain receptor 1 and β1 integrin regulate attachment to collagen
por: Staudinger, Lisa A., et al.
Publicado: (2013)

Overexpression of TGN38/41 leads to mislocalisation of γ‐adaptin
por: Reaves, Barbara, et al.
Publicado: (1994)

The FAT1 Cadherin Drives Vascular Smooth Muscle Cell Migration
por: Riascos-Bernal, Dario F., et al.
Publicado: (2023)

Collagen I–mediated up-regulation of N-cadherin requires cooperative signals from integrins and discoidin domain receptor 1
por: Shintani, Yasushi, et al.
Publicado: (2008)

The Fat1 cadherin integrates vascular smooth muscle cell growth and migration signals
por: Hou, Rong, et al.
Publicado: (2006)

Discoidin Domain Receptors: Potential Actors and Targets in Cancer
por: Rammal, Hassan, et al.
Publicado: (2016)

Collagen recognition and transmembrane signalling by discoidin domain receptors()
por: Carafoli, Federico, et al.
Publicado: (2013)

Recent Advances in the Role of Discoidin Domain Receptor Tyrosine Kinase 1 and Discoidin Domain Receptor Tyrosine Kinase 2 in Breast and Ovarian Cancer
por: Chen, Li, et al.
Publicado: (2021)

Discoidin domain receptor 1-deletion ameliorates fibrosis and promotes adipose tissue beiging, brown fat activity, and increased metabolic rate in a mouse model of cardiometabolic disease
por: Lino, Marsel, et al.
Publicado: (2020)

The Atypical Cadherin FAT1 Limits Mitochondrial Respiration and Proliferation of Vascular Smooth Muscle Cells
por: Riascos-Bernal, Dario F., et al.
Publicado: (2022)

HnRNP K mislocalisation is a novel protein pathology of frontotemporal lobar degeneration and ageing and leads to cryptic splicing
por: Bampton, Alexander, et al.
Publicado: (2021)

Crystallographic Insight into Collagen Recognition by Discoidin Domain Receptor 2
por: Carafoli, Federico, et al.
Publicado: (2009)

Corrigendum: Discoidin Domain Receptors: Potential Actors and Targets in Cancer
por: Rammal, Hassan, et al.
Publicado: (2016)

Inhibitors of Discoidin Domain Receptor (DDR) Kinases for Cancer and Inflammation
por: Denny, William A., et al.
Publicado: (2021)

Focusing on discoidin domain receptors in premalignant and malignant liver diseases
por: Gong, Hang, et al.
Publicado: (2023)

Discoidin I and discoidin II are localized differently in developing Dictyostelium discoideum
Publicado: (1983)

Smooth Muscle Hgs Deficiency Leads to Impaired Esophageal Motility
por: Chen, Jicheng, et al.
Publicado: (2015)

Expression of Concern: Discoidin Domain Receptors: Potential Actors and Targets in Cancer
Publicado: (2016)

Discoidin domain receptors: Microenvironment sensors that promote cellular migration and invasion
por: Itoh, Yoshifumi
Publicado: (2018)

Control of craniofacial development by the collagen receptor, discoidin domain receptor 2
por: Mohamed, Fatma F, et al.
Publicado: (2023)

Discoidin domain receptor regulates ensheathment, survival and caliber of peripheral axons
por: Corty, Megan M., et al.
Publicado: (2022)

Destabilisation, aggregation, toxicity and cytosolic mislocalisation of nucleophosmin regions associated with acute myeloid leukemia
por: Scognamiglio, Pasqualina Liana, et al.
Publicado: (2016)

N-Cadherin Induction by ECM Stiffness and FAK Overrides the Spreading Requirement for Proliferation of Vascular Smooth Muscle Cells
por: Mui, Keeley L., et al.
Publicado: (2015)

Impaired dermal wound healing in discoidin domain receptor 2-deficient mice associated with defective extracellular matrix remodeling
por: Olaso, Elvira, et al.
Publicado: (2011)

Discoidin Domain Receptor 1 Contributes to Tumorigenesis through Modulation of TGFBI Expression
por: Rudra-Ganguly, Nandini, et al.
Publicado: (2014)

Discoidin domain receptor 1 activity drives an aggressive phenotype in gastric carcinoma
por: Hur, Hoon, et al.
Publicado: (2017)

Phosphoproteomic analysis identifies insulin enhancement of discoidin domain receptor 2 phosphorylation
por: Iwai, Leo K., et al.
Publicado: (2013)

Discoidin Domain Receptors 1 Inhibition Alleviates Osteoarthritis via Enhancing Autophagy
por: Chou, Hsin-Chaio, et al.
Publicado: (2020)

N-Glycosylation of the Discoidin Domain Receptor Is Required for Axon Regeneration in Caenorhabditis elegans
por: Shimizu, Tatsuhiro, et al.
Publicado: (2019)

Discoidin domain receptors orchestrate cancer progression: A focus on cancer therapies
por: Gao, Yuan, et al.
Publicado: (2021)

Discoidin Domain Receptor 1 Expression in Colon Cancer: Roles and Prognosis Impact
por: Ben Arfi, Kaouther, et al.
Publicado: (2022)

Genetic and pharmacological tools to study the role of discoidin domain receptors in kidney disease
por: Borza, Corina M., et al.
Publicado: (2022)

Endothelial discoidin domain receptor 1 senses flow to modulate YAP activation
por: Liu, Jiayu, et al.
Publicado: (2023)

Cytosolic caspases mediate mislocalised SOD2 depletion in an in vitro model of chronic prion infection
por: Sinclair, Layla, et al.
Publicado: (2013)

p62 overexpression induces TDP-43 cytoplasmic mislocalisation, aggregation and cleavage and neuronal death
por: Foster, A. D., et al.
Publicado: (2021)

NOX4 downregulation leads to senescence of human vascular smooth muscle cells
por: Przybylska, Dorota, et al.
Publicado: (2016)

Mechanism of Hypoxia-Mediated Smooth Muscle Cell Proliferation Leading to Vascular Remodeling
por: Huang, Xiaojuan, et al.
Publicado: (2022)

Protective effects of genetic inhibition of Discoidin Domain Receptor 1 in experimental renal disease
por: Kerroch, Monique, et al.
Publicado: (2016)

Recombinant Collagen Engineered to Bind to Discoidin Domain Receptor Functions as a Receptor Inhibitor
por: An, Bo, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_tsc2qve3q17deojfus7j58rfkt