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MicroRNA-138 negatively regulates the hypoxia-inducible factor 1α to suppress melanoma growth and metastasis

Melanoma with rapid progression towards metastasis has become the deadliest form of skin cancer. However, the mechanism of melanoma growth and metastasis is still unclear. Here, we found that miRNA-138 was lowly expressed and hypoxia-inducible factor 1α (HIF1α) was highly expressed in patients’ mela...

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Detalles Bibliográficos
Autores principales: Qiu, Haijiang, Chen, Fangchao, Chen, Minjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737980/
https://www.ncbi.nlm.nih.gov/pubmed/31371307
http://dx.doi.org/10.1242/bio.042937