Cargando…

Diagnosis of epithelial ovarian cancer using a combined protein biomarker panel

BACKGROUND: An early detection tool for EOC was constructed from analysis of biomarker expression data from serum collected during the UKCTOCS. METHODS: This study included 49 EOC cases (19 Type I and 30 Type II) and 31 controls, representing 482 serial samples spanning seven years pre-diagnosis. A...

Descripción completa

Detalles Bibliográficos
Autores principales:	Russell, Matthew R., Graham, Ciaren, D’Amato, Alfonsina, Gentry-Maharaj, Aleksandra, Ryan, Andy, Kalsi, Jatinderpal K., Whetton, Anthony D., Menon, Usha, Jacobs, Ian, Graham, Robert L. J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738042/ https://www.ncbi.nlm.nih.gov/pubmed/31388184 http://dx.doi.org/10.1038/s41416-019-0544-0

Ejemplares similares

A combined biomarker panel shows improved sensitivity for the early detection of ovarian cancer allowing the identification of the most aggressive type II tumours
por: Russell, Matthew R, et al.
Publicado: (2017)

Novel risk models for early detection and screening of ovarian cancer
por: Russell, Matthew R., et al.
Publicado: (2016)

Protein Z: A putative novel biomarker for early detection of ovarian cancer
por: Russell, Matthew R., et al.
Publicado: (2016)

Socioeconomic Status and Ovarian Cancer Stage at Diagnosis: A Study Nested Within UKCTOCS
por: Karpinskyj, Chloe, et al.
Publicado: (2020)

Validity of self-reported hysterectomy: a prospective cohort study within the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS)
por: Gentry-Maharaj, Aleksandra, et al.
Publicado: (2014)

A quantitative performance study of two automatic methods for the diagnosis of ovarian cancer
por: Vázquez, Manuel A., et al.
Publicado: (2018)

Improved early detection of ovarian cancer using longitudinal multimarker models
por: Whitwell, Harry J., et al.
Publicado: (2020)

Socioeconomic indicators of health inequalities and female mortality: a nested cohort study within the United Kingdom Collaborative Trial of Ovarian Cancer Screening (UKCTOCS)
por: Bailey, Katharine, et al.
Publicado: (2015)

Changing trends in reproductive/lifestyle factors in UK women: descriptive study within the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS)
por: Gentry-Maharaj, Aleksandra, et al.
Publicado: (2017)

Evaluation of polygenic risk scores for ovarian cancer risk prediction in a prospective cohort study
por: Yang, Xin, et al.
Publicado: (2018)

Ovarian cancer symptoms, routes to diagnosis and survival – Population cohort study in the ‘no screen’ arm of the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS)
por: Dilley, James, et al.
Publicado: (2020)

Ovarian cancer screening—Current status, future directions()
por: Menon, Usha, et al.
Publicado: (2014)

Serial Patterns of Ovarian Cancer Biomarkers in a Prediagnosis Longitudinal Dataset
por: Blyuss, Oleg, et al.
Publicado: (2015)

Completeness and accuracy of national cancer and death registration for outcome ascertainment in trials—an ovarian cancer exemplar
por: Kalsi, Jatinderpal K., et al.
Publicado: (2021)

Association of skirt size and postmenopausal breast cancer risk in older women: a cohort study within the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS)
por: Fourkala, Evangelia-Ourania, et al.
Publicado: (2014)

Use and perceived efficacy of complementary and alternative medicines after discontinuation of hormone therapy: a nested United Kingdom Collaborative Trial of Ovarian Cancer Screening cohort study
por: Gentry-Maharaj, Aleksandra, et al.
Publicado: (2015)

Audit of transvaginal sonography of normal postmenopausal ovaries by sonographers from the United Kingdom Collaborative Trial of Ovarian Cancer Screening (UKCTOCS)
por: Stott, Will, et al.
Publicado: (2018)

Performance Characteristics of the Ultrasound Strategy during Incidence Screening in the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS)
por: Kalsi, Jatinderpal, et al.
Publicado: (2021)

Serum HE4 and diagnosis of ovarian cancer in postmenopausal women with adnexal masses
por: Gentry-Maharaj, Aleksandra, et al.
Publicado: (2020)

Multi-Marker Longitudinal Algorithms Incorporating HE4 and CA125 in Ovarian Cancer Screening of Postmenopausal Women
por: Gentry-Maharaj, Aleksandra, et al.
Publicado: (2020)

UKCTOCS update: applying insights of delayed effects in cancer screening trials to the long-term follow-up mortality analysis
por: Burnell, Matthew, et al.
Publicado: (2021)

Risk of chronic liver disease in post-menopausal women due to body mass index, alcohol and their interaction: a prospective nested cohort study within the United Kingdom Collaborative Trial of Ovarian Cancer Screening (UKCTOCS)
por: Trembling, Paul M, et al.
Publicado: (2017)

Long-Term Secondary Care Costs of Endometrial Cancer: A Prospective Cohort Study Nested within the United Kingdom Collaborative Trial of Ovarian Cancer Screening (UKCTOCS)
por: Pennington, Mark, et al.
Publicado: (2016)

Comprehensive epithelial tubo-ovarian cancer risk prediction model incorporating genetic and epidemiological risk factors
por: Lee, Andrew, et al.
Publicado: (2022)

The cost-effectiveness of screening for ovarian cancer: results from the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS)
por: Menon, Usha, et al.
Publicado: (2017)

Generation of a mouse SWATH-MS spectral library to quantify 10148 proteins involved in cell reprogramming
por: Ulanga, Uxue, et al.
Publicado: (2021)

Time to diagnosis of Type I or II invasive epithelial ovarian cancers: a multicentre observational study using patient questionnaire and primary care records
por: Lim, AWW, et al.
Publicado: (2015)

An Epigenetic Signature in Peripheral Blood Predicts Active Ovarian Cancer
por: Teschendorff, Andrew E., et al.
Publicado: (2009)

Ovarian cancer population screening and mortality after long-term follow-up in the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS): a randomised controlled trial
por: Menon, Usha, et al.
Publicado: (2021)

Population Study of Ovarian Cancer Risk Prediction for Targeted Screening and Prevention
por: Gaba, Faiza, et al.
Publicado: (2020)

Serial endometrial thickness and risk of non‐endometrial hormone‐dependent cancers in postmenopausal women in UK Collaborative Trial of Ovarian Cancer Screening
por: Burnell, M., et al.
Publicado: (2020)

Colorectal cancer ascertainment through cancer registries, hospital episode statistics, and self-reporting compared to confirmation by clinician: A cohort study nested within the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS)
por: Thomas, Darren S., et al.
Publicado: (2019)

Testing breast cancer serum biomarkers for early detection and prognosis in pre-diagnosis samples
por: Kazarian, Anna, et al.
Publicado: (2017)

Impact on mortality and cancer incidence rates of using random invitation from population registers for recruitment to trials
por: Burnell, Matthew, et al.
Publicado: (2011)

Cancer-associated autoantibodies to MUC1 and MUC4—A blinded case–control study of colorectal cancer in UK collaborative trial of ovarian cancer screening
por: Pedersen, Johannes W, et al.
Publicado: (2014)

Discovery and validation of serum glycoprotein biomarkers for high grade serous ovarian cancer
por: Dutt, Mriga, et al.
Publicado: (2023)

Identifying hopelessness in population research: a validation study of two brief measures of hopelessness
por: Fraser, Lindsay, et al.
Publicado: (2014)

Discovery of serum biomarkers of ovarian cancer using complementary proteomic profiling strategies
por: Timms, John F., et al.
Publicado: (2014)

The Enhanced Liver Fibrosis test is associated with liver-related outcomes in postmenopausal women with risk factors for liver disease
por: Trembling, Paul M., et al.
Publicado: (2020)

Risk Algorithm Using Serial Biomarker Measurements Doubles the Number of Screen-Detected Cancers Compared With a Single-Threshold Rule in the United Kingdom Collaborative Trial of Ovarian Cancer Screening
por: Menon, Usha, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_qfilos3a749o908b6pbbv9ta5u