Can PD-L1 expression evaluated by biopsy sample accurately reflect its expression in the whole tumour in gastric cancer?

Programmed death ligand 1 (PD-L1) expression as a predictive biomarker for programmed cell death 1 (PD-1) inhibitor efficacy in gastric cancer (GC) remains controversial. We hypothesised that the conflicting results may be due to the inaccurate assessment of PD-L1 expression using biopsy samples. A...

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Detalles Bibliográficos
Autores principales: Yamashita, Kohei, Iwatsuki, Masaaki, Harada, Kazuto, Koga, Yuki, Kiyozumi, Yuki, Eto, Kojiro, Hiyoshi, Yukiharu, Ishimoto, Takatsugu, Iwagami, Shiro, Baba, Yoshifumi, Miyamoto, Yuji, Yoshida, Naoya, Komohara, Yoshihiro, Ajani, Jaffer A., Baba, Hideo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738080/
https://www.ncbi.nlm.nih.gov/pubmed/31285589
http://dx.doi.org/10.1038/s41416-019-0515-5

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