Molecular portrait of high alpha-fetoprotein in hepatocellular carcinoma: implications for biomarker-driven clinical trials

The clinical utility of serum alpha-fetoprotein (AFP) in patients with hepatocellular carcinoma (HCC) is widely recognised. However, a clear understanding of the mechanisms of AFP overexpression and the molecular traits of patients with AFP-high tumours are not known. We assessed transcriptome data,...

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Detalles Bibliográficos
Autores principales: Montal, Robert, Andreu-Oller, Carmen, Bassaganyas, Laia, Esteban-Fabró, Roger, Moran, Sebastián, Montironi, Carla, Moeini, Agrin, Pinyol, Roser, Peix, Judit, Cabellos, Laia, Villanueva, Augusto, Sia, Daniela, Mazzaferro, Vincenzo, Esteller, Manel, Llovet, Josep M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738090/
https://www.ncbi.nlm.nih.gov/pubmed/31285588
http://dx.doi.org/10.1038/s41416-019-0513-7

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