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The anaphase-promoting complex/cyclosome: a new promising target in diffuse large B-cell lymphoma and mantle cell lymphoma

BACKGROUND: The aggressive B-cell non-Hodgkin lymphomas diffuse large B-cell lymphoma (DLBCL) and mantle cell lymphoma (MCL) are characterised by a high proliferation rate. The anaphase-promoting complex/cyclosome (APC/C) and its co-activators Cdc20 and Cdh1 represent an important checkpoint in mito...

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Detalles Bibliográficos
Autores principales: Maes, Anke, Maes, Ken, De Raeve, Hendrik, De Smedt, Eva, Vlummens, Philip, Szablewski, Vanessa, Devin, Julie, Faict, Sylvia, De Veirman, Kim, Menu, Eline, Offner, Fritz, Spaargaren, Marcel, Moreaux, Jérôme, Vanderkerken, Karin, Van Valckenborgh, Els, De Bruyne, Elke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738099/
https://www.ncbi.nlm.nih.gov/pubmed/31089208
http://dx.doi.org/10.1038/s41416-019-0471-0

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