Moving from one to many: insights from the growing list of pleiotropic cancer risk genes

Pleiotropy, a phenomenon in which a single gene affects multiple phenotypes, is becoming very common among different cancer types and cancer-related phenotypes, such as those in hormonal, cardiometabolic and inflammatory/immune conditions. The discovery of pleiotropic associations can improve our un...

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Detalles Bibliográficos
Autores principales: Bien, Stephanie A., Peters, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Editorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738109/
https://www.ncbi.nlm.nih.gov/pubmed/31110328
http://dx.doi.org/10.1038/s41416-019-0475-9
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Peters, Ulrike
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Peters, Ulrike
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description Pleiotropy, a phenomenon in which a single gene affects multiple phenotypes, is becoming very common among different cancer types and cancer-related phenotypes, such as those in hormonal, cardiometabolic and inflammatory/immune conditions. The discovery of pleiotropic associations can improve our understanding of cancer and help to target investigation of genes with greater clinical relevance.
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spelling pubmed-67381092019-09-12 Moving from one to many: insights from the growing list of pleiotropic cancer risk genes Bien, Stephanie A. Peters, Ulrike Br J Cancer Editorial Pleiotropy, a phenomenon in which a single gene affects multiple phenotypes, is becoming very common among different cancer types and cancer-related phenotypes, such as those in hormonal, cardiometabolic and inflammatory/immune conditions. The discovery of pleiotropic associations can improve our understanding of cancer and help to target investigation of genes with greater clinical relevance. Nature Publishing Group UK 2019-05-21 2019-06-11 /pmc/articles/PMC6738109/ /pubmed/31110328 http://dx.doi.org/10.1038/s41416-019-0475-9 Text en © The Author(s) 2019 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Editorial
Bien, Stephanie A.
Peters, Ulrike
Moving from one to many: insights from the growing list of pleiotropic cancer risk genes
title Moving from one to many: insights from the growing list of pleiotropic cancer risk genes
title_full Moving from one to many: insights from the growing list of pleiotropic cancer risk genes
title_fullStr Moving from one to many: insights from the growing list of pleiotropic cancer risk genes
title_full_unstemmed Moving from one to many: insights from the growing list of pleiotropic cancer risk genes
title_short Moving from one to many: insights from the growing list of pleiotropic cancer risk genes
title_sort moving from one to many: insights from the growing list of pleiotropic cancer risk genes
topic Editorial
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738109/
https://www.ncbi.nlm.nih.gov/pubmed/31110328
http://dx.doi.org/10.1038/s41416-019-0475-9
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