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Perforating Granuloma Annulare Appearing as a Psoriasiform Lesion
We present a 54-year-old Caucasian female with a history of diabetes mellitus, multiple sclerosis, and ulcerative colitis who presented with nail dystrophy, polyarthralgia in her hands and hips, myalgia, proximal myopathy, dactylitis, and psoriasiform-appearing progressive, painful plaques on the do...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738183/ https://www.ncbi.nlm.nih.gov/pubmed/31543770 http://dx.doi.org/10.1159/000501875 |
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author | Witkoff, Benjamin M. Ivanov, Nedyalko N. Trotter, Shannon C. |
author_facet | Witkoff, Benjamin M. Ivanov, Nedyalko N. Trotter, Shannon C. |
author_sort | Witkoff, Benjamin M. |
collection | PubMed |
description | We present a 54-year-old Caucasian female with a history of diabetes mellitus, multiple sclerosis, and ulcerative colitis who presented with nail dystrophy, polyarthralgia in her hands and hips, myalgia, proximal myopathy, dactylitis, and psoriasiform-appearing progressive, painful plaques on the dorsal aspect of her hands. Histologic examination of the lesion from the left index finger revealed an interstitial and necrobiotic granulomatous dermatitis with connective tissue mucin deposition associated with a perivascular lymphoid infiltrate. Additionally, there was focal transepidermal elimination of the necrobiotic material. She was diagnosed with perforating granuloma annulare (PGA). We are unaware of any other cases of PGA in the literature with this presentation. |
format | Online Article Text |
id | pubmed-6738183 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | S. Karger AG |
record_format | MEDLINE/PubMed |
spelling | pubmed-67381832019-09-22 Perforating Granuloma Annulare Appearing as a Psoriasiform Lesion Witkoff, Benjamin M. Ivanov, Nedyalko N. Trotter, Shannon C. Case Rep Dermatol Single Case We present a 54-year-old Caucasian female with a history of diabetes mellitus, multiple sclerosis, and ulcerative colitis who presented with nail dystrophy, polyarthralgia in her hands and hips, myalgia, proximal myopathy, dactylitis, and psoriasiform-appearing progressive, painful plaques on the dorsal aspect of her hands. Histologic examination of the lesion from the left index finger revealed an interstitial and necrobiotic granulomatous dermatitis with connective tissue mucin deposition associated with a perivascular lymphoid infiltrate. Additionally, there was focal transepidermal elimination of the necrobiotic material. She was diagnosed with perforating granuloma annulare (PGA). We are unaware of any other cases of PGA in the literature with this presentation. S. Karger AG 2019-08-06 /pmc/articles/PMC6738183/ /pubmed/31543770 http://dx.doi.org/10.1159/000501875 Text en Copyright © 2019 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission. |
spellingShingle | Single Case Witkoff, Benjamin M. Ivanov, Nedyalko N. Trotter, Shannon C. Perforating Granuloma Annulare Appearing as a Psoriasiform Lesion |
title | Perforating Granuloma Annulare Appearing as a Psoriasiform Lesion |
title_full | Perforating Granuloma Annulare Appearing as a Psoriasiform Lesion |
title_fullStr | Perforating Granuloma Annulare Appearing as a Psoriasiform Lesion |
title_full_unstemmed | Perforating Granuloma Annulare Appearing as a Psoriasiform Lesion |
title_short | Perforating Granuloma Annulare Appearing as a Psoriasiform Lesion |
title_sort | perforating granuloma annulare appearing as a psoriasiform lesion |
topic | Single Case |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738183/ https://www.ncbi.nlm.nih.gov/pubmed/31543770 http://dx.doi.org/10.1159/000501875 |
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