Cargando…
G2019S Variation in LRRK2: An Ideal Model for the Study of Parkinson’s Disease?
Parkinson’s disease (PD) is the second most common neurodegenerative disorder and has plagued humans for more than 200 years. The etiology and detailed pathogenesis of PD is unclear, but is currently believed to be the result of the interaction between genetic and environmental factors. Studies have...
Autores principales: | Ren, Chao, Ding, Yu, Wei, Shizhuang, Guan, Lina, Zhang, Caiyi, Ji, Yongqiang, Wang, Fen, Yin, Shaohua, Yin, Peiyuan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738350/ https://www.ncbi.nlm.nih.gov/pubmed/31551736 http://dx.doi.org/10.3389/fnhum.2019.00306 |
Ejemplares similares
-
Association of Dual LRRK2 G2019S and GBA Variations With Parkinson Disease Progression
por: Ortega, Roberto A., et al.
Publicado: (2021) -
Synaptic function is modulated by LRRK2 and glutamate release is increased in cortical neurons of G2019S LRRK2 knock-in mice
por: Beccano-Kelly, Dayne A., et al.
Publicado: (2014) -
G2019S LRRK2 Mutation Enhances MPP(+)-Induced Inflammation of Human Induced Pluripotent Stem Cells-Differentiated Dopaminergic Neurons
por: Chen, Ying, et al.
Publicado: (2022) -
Origins of Parkinson’s Disease in Brain Development: Insights From Early and Persistent Effects of LRRK2-G2019S on Striatal Circuits
por: Huntley, George W., et al.
Publicado: (2020) -
Glial Nrf2 signaling mediates the neuroprotection exerted by Gastrodia elata Blume in Lrrk2-G2019S Parkinson’s disease
por: Lin, Yu-En, et al.
Publicado: (2021)