Pharmacokinetics of Sublingual Buprenorphine Tablets Following Single and Multiple Doses in Chinese Participants With and Without Opioid Use Disorder

BACKGROUND: Two phase I studies assessed the pharmacokinetics of buprenorphine, its metabolite norbuprenorphine, and naloxone following administration of buprenorphine/naloxone sublingual tablets in Chinese participants. METHODS: In the first phase I, open-label, single ascending-dose (SAD) study, 8...

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Detalles Bibliográficos
Autores principales: Dong, Ruihua, Wang, Hongyun, Li, Dandan, Lang, Liwei, Gray, Frank, Liu, Yongzhen, Laffont, Celine M., Young, Malcolm, Jiang, Ji, Liu, Zeyuan, Learned, Susan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738359/
https://www.ncbi.nlm.nih.gov/pubmed/31197606
http://dx.doi.org/10.1007/s40268-019-0277-9

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