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DNA methylation-based estimator of telomere length

Telomere length (TL) is associated with several aging-related diseases. Here, we present a DNA methylation estimator of TL (DNAmTL) based on 140 CpGs. Leukocyte DNAmTL is applicable across the entire age spectrum and is more strongly associated with age than measured leukocyte TL (LTL) (r ~-0.75 for...

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Detalles Bibliográficos
Autores principales:	Lu, Ake T., Seeboth, Anne, Tsai, Pei-Chien, Sun, Dianjianyi, Quach, Austin, Reiner, Alex P., Kooperberg, Charles, Ferrucci, Luigi, Hou, Lifang, Baccarelli, Andrea A., Li, Yun, Harris, Sarah E., Corley, Janie, Taylor, Adele, Deary, Ian J., Stewart, James D., Whitsel, Eric A., Assimes, Themistocles L., Chen, Wei, Li, Shengxu, Mangino, Massimo, Bell, Jordana T., Wilson, James G., Aviv, Abraham, Marioni, Riccardo E., Raj, Kenneth, Horvath, Steve
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738410/ https://www.ncbi.nlm.nih.gov/pubmed/31422385 http://dx.doi.org/10.18632/aging.102173

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