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MiR-27a promotes the autophagy and apoptosis of IL-1β treated-articular chondrocytes in osteoarthritis through PI3K/AKT/mTOR signaling

Osteoarthritis (OA) is a common degenerative joint disorder, which involves articular cartilage degeneration as well as joint inflammatory reactions. The recent studies have identified microRNA (miRNA) as one of the epigenetic mechanisms for the regulation of gene expression. Here we aim to reveal t...

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Detalles Bibliográficos
Autores principales: Cai, Chen, Min, Shaoxiong, Yan, Bo, Liu, Wen, Yang, Xiao, Li, Liuxun, Wang, Ting, Jin, Anmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738432/
https://www.ncbi.nlm.nih.gov/pubmed/31460867
http://dx.doi.org/10.18632/aging.102194