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MicroRNA-181a protects against pericyte apoptosis via directly targeting FOXO1: implication for ameliorated cognitive deficits in APP/PS1 mice
MicroRNAs (miRNAs) have emerged as critical regulators in the pathology of Alzheimer’s disease (AD). MiR-181a is associated with hippocampal memory formation and aberrantly expressed in patients with mild cognitive impairment (MCI), however, little is known about its role and underlying mechanism in...
Autores principales: | Wu, Qingbin, Yuan, Xiaochen, Bai, Jing, Han, Ruiqin, Li, Zhigang, Zhang, Honggang, Xiu, Ruijuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738434/ https://www.ncbi.nlm.nih.gov/pubmed/31467256 http://dx.doi.org/10.18632/aging.102171 |
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