Cargando…

The protective role of microRNA-140-5p in synovial injury of rats with knee osteoarthritis via inactivating the TLR4/Myd88/NF-κB signaling pathway

Objective: Recently, many studies have revealed the effect of microRNAs (miRNAs) in knee osteoarthritis (KOA). This study aims to explore the role of miR-140-5p in protective effects and mechanisms of synovial injury of rats with KOA via regulating the TLR4/Myd88/NF-κB signaling pathway. Methods: Th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Xiaoqiang, Qiao, Feng, Xue, Peng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738526/ https://www.ncbi.nlm.nih.gov/pubmed/31345099 http://dx.doi.org/10.1080/15384101.2019.1647025

Ejemplares similares

Tendon-regulating and bone-setting manipulation promotes the recovery of synovial inflammation in rabbits with knee osteoarthritis via the TLR4–MyD88–NF-κB signaling pathway
por: Jin, Xiangyu, et al.
Publicado: (2023)

The mechanism of medial collateral ligament repair in knee osteoarthritis based on the TLR4/MyD88/NF-κB inflammatory signaling pathway
por: Li, Zhiyong, et al.
Publicado: (2020)

Zhuifeng tougu capsules inhibit the TLR4/MyD88/NF-κB signaling pathway and alleviate knee osteoarthritis: In vitro and in vivo experiments
por: Xu, Xiaotong, et al.
Publicado: (2022)

Non-weight-bearing exercise attenuates papain-induced knee osteoarthritis in rats via the TLR4/MyD88/NF-κB signaling pathway
por: Wang, Kewen, et al.
Publicado: (2023)

Expression of TLR4-MyD88 and NF-κB in the Iris during Endotoxin-Induced Uveitis
por: Li, Shang, et al.
Publicado: (2010)

The Effect of TLR9, MyD88, and NF-κB p65 in Systemic Lupus Erythematosus
por: Wang, Huanan, et al.
Publicado: (2022)

Phycocyanin attenuates pulmonary fibrosis via the TLR2-MyD88-NF-κB signaling pathway
por: Li, Chengcheng, et al.
Publicado: (2017)

The role of TLR4/MyD88/NF‐κB pathway in periodontitis‐induced liver inflammation of rats
por: Yue, Yiyun, et al.
Publicado: (2020)

Loganin attenuates interleukin-1β-induced chondrocyte inflammation, cartilage degeneration, and rat synovial inflammation by regulating TLR4/MyD88/NF-κB
por: Wan, Haishan, et al.
Publicado: (2022)

Upregulation of miRNA-140-5p inhibits inflammatory cytokines in acute lung injury through the MyD88/NF-κB signaling pathway by targeting TLR4
por: Yang, Ye, et al.
Publicado: (2018)

Oxymatrine Downregulates TLR4, TLR2, MyD88, and NF-κB and Protects Rat Brains against Focal Ischemia
por: Fan, Hongguang, et al.
Publicado: (2009)

Exercise Therapy Downregulates the Overexpression of TLR4, TLR2, MyD88 and NF-κB after Cerebral Ischemia in Rats
por: Ma, Yuewen, et al.
Publicado: (2013)

Baishouwu Extract Suppresses the Development of Hepatocellular Carcinoma via TLR4/MyD88/NF-κB Pathway
por: Ding, Yong-fang, et al.
Publicado: (2019)

Lipoxin suppresses inflammation via the TLR4/MyD88/NF‐κB pathway in periodontal ligament cells
por: Ali, Muhanad, et al.
Publicado: (2019)

Tacrolimus alleviates LPS‐induced AKI by inhibiting TLR4/MyD88/NF‐κB signalling in mice
por: Hu, Xueqing, et al.
Publicado: (2021)

Vinpocetine alleviate cerebral ischemia/reperfusion injury by down-regulating TLR4/MyD88/NF-κB signaling
por: Wu, Li-Rong, et al.
Publicado: (2017)

Dexmedetomidine Protects Cardiomyocytes against Hypoxia/Reoxygenation Injury by Suppressing TLR4-MyD88-NF-κB Signaling
por: Gao, Jin-meng, et al.
Publicado: (2017)

LIGHT aggravates sepsis‐associated acute kidney injury via TLR4‐MyD88‐NF‐κB pathway
por: Zhong, Yu, et al.
Publicado: (2020)

Exercise Training Attenuates Hypertension Through TLR4/MyD88/NF-κB Signaling in the Hypothalamic Paraventricular Nucleus
por: Qi, Jie, et al.
Publicado: (2019)

The TLR4-MyD88-NF-κB pathway is involved in sIgA-mediated IgA nephropathy
por: Zhang, Junjun, et al.
Publicado: (2020)

Selective targeting of the TLR2/MyD88/NF-κB pathway reduces α-synuclein spreading in vitro and in vivo
por: Dutta, Debashis, et al.
Publicado: (2021)

The Protective Effect of Anethole against Renal Ischemia/Reperfusion: The Role of the TLR2,4/MYD88/NFκB Pathway
por: Mohamed, Maged Elsayed, et al.
Publicado: (2022)

Synergy of TLR3 and 7 ligands significantly enhances function of DCs to present inactivated PRRSV antigen through TRIF/MyD88-NF-κB signaling pathway
por: Hu, Yue, et al.
Publicado: (2016)

Lipopolysaccharide-induced NF-κB nuclear translocation is primarily dependent on MyD88, but TNFα expression requires TRIF and MyD88
por: Sakai, Jiro, et al.
Publicado: (2017)

Sevoflurane alleviates LPS-induced acute lung injury via the microRNA-27a-3p/TLR4/MyD88/NF-κB signaling pathway
por: Wang, Yunfei, et al.
Publicado: (2019)

Confirmation of inhibitingTLR4/MyD88/NF-κB Signalling Pathway by Duhuo Jisheng Decoction on Osteoarthritis: A Network Pharmacology Approach-Integrated Experimental Study
por: Liu, Linglong, et al.
Publicado: (2022)

Circular RNA MELK Promotes Chondrocyte Apoptosis and Inhibits Autophagy in Osteoarthritis by Regulating MYD88/NF-κB Signaling Axis through MicroRNA-497-5p
por: Zhang, Yingchi, et al.
Publicado: (2022)

Isovitexin alleviates acute gouty arthritis in rats by inhibiting inflammation via the TLR4/MyD88/NF-κB pathway
por: Sun, Xiujiang, et al.
Publicado: (2021)

l-Isoleucine Administration Alleviates DSS-Induced Colitis by Regulating TLR4/MyD88/NF-κB Pathway in Rats
por: Mao, Xiangbing, et al.
Publicado: (2022)

Baicalin Inhibits Inflammation in Rats with Chronic Obstructive Pulmonary Disease by the TLR2/MYD88/NF-κBp65 Signaling Pathway
por: Ju, Jiangang, et al.
Publicado: (2022)

Inhibition of Mogroside IIIE on isoproterenol-induced myocardial fibrosis through the TLR4/MyD88/NF-κB signaling pathway
por: Yanan, Shi, et al.
Publicado: (2023)

Astaxanthin protects against early acute kidney injury in severely burned rats by inactivating the TLR4/MyD88/NF-κB axis and upregulating heme oxygenase-1
por: Guo, Songxue, et al.
Publicado: (2021)

Implication of microRNA-140 in osteoarthritis
por: Martel-Pelletier, Johanne
Publicado: (2012)

MicroRNA-93 contributes to the suppression of lung inflammatory responses in LPS-induced acute lung injury in mice via the TLR4/MyD88/NF-κB signaling pathway
por: Gao, Hu, et al.
Publicado: (2020)

MicroRNA-155 influences cell damage in ischemic stroke via TLR4/MYD88 signaling pathway
por: Chen, Wei, et al.
Publicado: (2021)

TLR4‐IN‐C34 protects against acute kidney injury via modulating TLR4/MyD88/NF-κb axis, MAPK, and apoptosis
por: Abdelsalam, Hadeer M., et al.
Publicado: (2022)

Soyasaponins reduce inflammation by downregulating MyD88 expression and suppressing the recruitments of TLR4 and MyD88 into lipid rafts
por: Chen, Junbin, et al.
Publicado: (2020)

Positive Correlation between Enhanced Expression of TLR4/MyD88/NF-κB with Insulin Resistance in Placentae of Gestational Diabetes Mellitus
por: Feng, Hui, et al.
Publicado: (2016)

Antipruritic effects of electroacupuncture on morphine-induced pruritus model mice through the TLR2/4-MyD88-NF-κB pathway
por: Ye, Yu Shan, et al.
Publicado: (2019)

Isoforskolin and forskolin attenuate lipopolysaccharide‐induced inflammation through TLR4/MyD88/NF‐κB cascades in human mononuclear leukocytes
por: Du, Xiaohua, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_5temudaj720j5r0okrftisvb6h