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Lupus Autoimmunity and Metabolic Parameters Are Exacerbated Upon High Fat Diet-Induced Obesity Due to TLR7 Signaling

Systemic lupus erythematosus (SLE) patients have increased prevalence of metabolic syndrome but the underlying mechanisms are unknown. Toll-like receptor 7 (TLR7) that detects single stranded-RNA plays a key role in antimicrobial host defense and also contributes to the initiation and progression of...

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Detalles Bibliográficos
Autores principales:	Hanna Kazazian, Noël, Wang, Yawen, Roussel-Queval, Annie, Marcadet, Laetitia, Chasson, Lionel, Laprie, Caroline, Desnues, Benoit, Charaix, Jonathan, Irla, Magali, Alexopoulou, Lena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738575/ https://www.ncbi.nlm.nih.gov/pubmed/31552019 http://dx.doi.org/10.3389/fimmu.2019.02015

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