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A nanobody targeting the translocated intimin receptor inhibits the attachment of enterohemorrhagic E. coli to human colonic mucosa

Enterohemorrhagic E. coli (EHEC) is a human intestinal pathogen that causes hemorrhagic colitis and hemolytic uremic syndrome. No vaccines or specific therapies are currently available to prevent or treat these infections. EHEC tightly attaches to the intestinal epithelium by injecting the intimin r...

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Detalles Bibliográficos
Autores principales:	Ruano-Gallego, David, Yara, Daniel A., Di Ianni, Lorenza, Frankel, Gad, Schüller, Stephanie, Fernández, Luis Ángel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738647/ https://www.ncbi.nlm.nih.gov/pubmed/31465434 http://dx.doi.org/10.1371/journal.ppat.1008031

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