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Identification of Antibiotic Administration as a Potentially Novel Factor Associated With Tacrolimus Trough Variability in Kidney Transplant Recipients: A Preliminary Study
Tacrolimus trough variability is an important risk factor for kidney allograft outcomes. Recent evidence suggests that the gut microbiota is associated with tacrolimus dosing requirements and direct metabolism of tacrolimus. We hypothesize that administration of antibiotics, which are known to alter...
Autores principales: | Zheng, YuanPu, Masand, Anjali, Wagner, Michael, Kapur, Sandip, Dadhania, Darshana, Lubetzky, Michelle, Lee, John Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739039/ https://www.ncbi.nlm.nih.gov/pubmed/31579813 http://dx.doi.org/10.1097/TXD.0000000000000930 |
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