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Identification of Antibiotic Administration as a Potentially Novel Factor Associated With Tacrolimus Trough Variability in Kidney Transplant Recipients: A Preliminary Study

Tacrolimus trough variability is an important risk factor for kidney allograft outcomes. Recent evidence suggests that the gut microbiota is associated with tacrolimus dosing requirements and direct metabolism of tacrolimus. We hypothesize that administration of antibiotics, which are known to alter...

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Detalles Bibliográficos
Autores principales: Zheng, YuanPu, Masand, Anjali, Wagner, Michael, Kapur, Sandip, Dadhania, Darshana, Lubetzky, Michelle, Lee, John Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739039/
https://www.ncbi.nlm.nih.gov/pubmed/31579813
http://dx.doi.org/10.1097/TXD.0000000000000930

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