Deconvolution of transcriptional networks identifies TCF4 as a master regulator in schizophrenia

Applying tissue-specific deconvolution of transcriptional networks to identify their master regulators (MRs) in neuropsychiatric disorders has been largely unexplored. Here, using two schizophrenia (SCZ) case-control RNA-seq datasets, one on postmortem dorsolateral prefrontal cortex (DLPFC) and anot...

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Detalles Bibliográficos
Autores principales: Doostparast Torshizi, Abolfazl, Armoskus, Chris, Zhang, Hanwen, Forrest, Marc P., Zhang, Siwei, Souaiaia, Tade, Evgrafov, Oleg V., Knowles, James A., Duan, Jubao, Wang, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739105/
https://www.ncbi.nlm.nih.gov/pubmed/31535015
http://dx.doi.org/10.1126/sciadv.aau4139

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