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Optimization of Cancer Treatment in the Frequency Domain
Thorough exploration of alternative dosing frequencies is often not performed in conventional pharmacometrics approaches. Quantitative systems pharmacology (QSP) can provide novel insights into optimal dosing regimen and drug behaviors which could add a new dimension to the design of novel treatment...
Autores principales: | Schulthess, Pascal, Rottschäfer, Vivi, Yates, James W. T., van der Graaf, Piet H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739279/ https://www.ncbi.nlm.nih.gov/pubmed/31512089 http://dx.doi.org/10.1208/s12248-019-0372-4 |
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