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A genome-wide screen for human salicylic acid (SA)-binding proteins reveals targets through which SA may influence development of various diseases

Salicylic acid (SA) is the major metabolite and active ingredient of aspirin; both compounds reduce pain, fever, and inflammation. Despite over a century of research, aspirin/SA’s mechanism(s) of action is still only partially understood. Here we report the results of a genome-wide, high-throughput...

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Detalles Bibliográficos
Autores principales: Choi, Hyong Woo, Wang, Lei, Powell, Adrian F., Strickler, Susan R., Wang, Dekai, Dempsey, D’Maris A., Schroeder, Frank C., Klessig, Daniel F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739329/
https://www.ncbi.nlm.nih.gov/pubmed/31511554
http://dx.doi.org/10.1038/s41598-019-49234-6