Chronic Pressure Overload Results in Deficiency of Mitochondrial Membrane Transporter ABCB7 Which Contributes to Iron Overload, Mitochondrial Dysfunction, Metabolic Shift and Worsens Cardiac Function

We examined the hitherto unexplored role of mitochondrial transporters and iron metabolism in advancing metabolic and mitochondrial dysfunction in the heart during long term pressure overload. We also investigated the link between mitochondrial dysfunction and fluctuation in mitochondrial transporte...

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Detalles Bibliográficos
Autores principales: Kumar, Vikas, A., Aneesh Kumar, Sanawar, Rahul, Jaleel, Abdul, Santhosh Kumar, T. R., Kartha, C. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739357/
https://www.ncbi.nlm.nih.gov/pubmed/31511561
http://dx.doi.org/10.1038/s41598-019-49666-0

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