Prion protein modulates endothelial to mesenchyme-like transition in trabecular meshwork cells: Implications for primary open angle glaucoma

Endothelial-to-mesenchyme-like transition (Endo-MT) of trabecular meshwork (TM) cells is known to be associated with primary open angle glaucoma (POAG). Here, we investigated whether the prion protein (PrP(C)), a neuronal protein known to modulate epithelial-to-mesenchymal transition in a variety of...

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Detalles Bibliográficos
Autores principales: Ashok, Ajay, Kang, Min H., Wise, Aaron S., Pattabiraman, P., Johnson, William M., Lonigro, Michael, Ravikumar, Ranjana, Rhee, Douglas J., Singh, Neena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739364/
https://www.ncbi.nlm.nih.gov/pubmed/31511544
http://dx.doi.org/10.1038/s41598-019-49482-6

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