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miR-146a attenuates apoptosis and modulates autophagy by targeting TAF9b/P53 pathway in doxorubicin-induced cardiotoxicity
Clinical therapy of doxorubicin (DOX) is limited due to its cardiotoxicity. miR-146a was proved as a protective factor in many cardiovascular diseases, but its role in chronic DOX-induced cardiotoxicity is unclear. The objective of this study was to demonstrate the role of miR-146a in low-dose long-...
Autores principales: | Pan, Jian-An, Tang, Yong, Yu, Jian-Ying, Zhang, Hui, Zhang, Jun-Feng, Wang, Chang-Qian, Gu, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739392/ https://www.ncbi.nlm.nih.gov/pubmed/31511497 http://dx.doi.org/10.1038/s41419-019-1901-x |
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