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Breastfeeding and maternal cardiovascular risk factors: 1982 Pelotas Birth Cohort

This study evaluated the association of breastfeeding duration with maternal metabolic cardiovascular risk factors among women who have been prospectively followed since birth in a southern Brazilian city. In the unadjusted analysis, total cholesterol was higher among women who never breastfed in re...

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Autores principales: Lima, Natália P., Bassani, Diego G., Magalhães, Elma Izze S., Barros, Fernando C., Horta, Bernardo L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739402/
https://www.ncbi.nlm.nih.gov/pubmed/31511590
http://dx.doi.org/10.1038/s41598-019-49576-1
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author Lima, Natália P.
Bassani, Diego G.
Magalhães, Elma Izze S.
Barros, Fernando C.
Horta, Bernardo L.
author_facet Lima, Natália P.
Bassani, Diego G.
Magalhães, Elma Izze S.
Barros, Fernando C.
Horta, Bernardo L.
author_sort Lima, Natália P.
collection PubMed
description This study evaluated the association of breastfeeding duration with maternal metabolic cardiovascular risk factors among women who have been prospectively followed since birth in a southern Brazilian city. In the unadjusted analysis, total cholesterol was higher among women who never breastfed in relation to those who breastfed ≥12 months. Among women with one livebirth, a shorter duration of breastfeeding was associated with lower HDL, while those with two or more livebirths and that breastfed for shorter time presented lower pulse wave velocity, glycaemia and non-HDL measures. After controlling for confounding variables, the magnitude of these associations decreased, and the confidence intervals included the reference. Concerning the duration of breastfeeding of the last child, the analysis was stratified by time since last birth. After controlling for confounders, systolic blood pressure was lower among women who breastfed 3 to <6 months and had a child within the last five years in relation to those who breastfed ≥6, but no clear trend was observed (p = 0.17). In conclusion, our findings suggest that there is no association between lactation and maternal cardiometabolic risk factors.
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spelling pubmed-67394022019-09-22 Breastfeeding and maternal cardiovascular risk factors: 1982 Pelotas Birth Cohort Lima, Natália P. Bassani, Diego G. Magalhães, Elma Izze S. Barros, Fernando C. Horta, Bernardo L. Sci Rep Article This study evaluated the association of breastfeeding duration with maternal metabolic cardiovascular risk factors among women who have been prospectively followed since birth in a southern Brazilian city. In the unadjusted analysis, total cholesterol was higher among women who never breastfed in relation to those who breastfed ≥12 months. Among women with one livebirth, a shorter duration of breastfeeding was associated with lower HDL, while those with two or more livebirths and that breastfed for shorter time presented lower pulse wave velocity, glycaemia and non-HDL measures. After controlling for confounding variables, the magnitude of these associations decreased, and the confidence intervals included the reference. Concerning the duration of breastfeeding of the last child, the analysis was stratified by time since last birth. After controlling for confounders, systolic blood pressure was lower among women who breastfed 3 to <6 months and had a child within the last five years in relation to those who breastfed ≥6, but no clear trend was observed (p = 0.17). In conclusion, our findings suggest that there is no association between lactation and maternal cardiometabolic risk factors. Nature Publishing Group UK 2019-09-11 /pmc/articles/PMC6739402/ /pubmed/31511590 http://dx.doi.org/10.1038/s41598-019-49576-1 Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Lima, Natália P.
Bassani, Diego G.
Magalhães, Elma Izze S.
Barros, Fernando C.
Horta, Bernardo L.
Breastfeeding and maternal cardiovascular risk factors: 1982 Pelotas Birth Cohort
title Breastfeeding and maternal cardiovascular risk factors: 1982 Pelotas Birth Cohort
title_full Breastfeeding and maternal cardiovascular risk factors: 1982 Pelotas Birth Cohort
title_fullStr Breastfeeding and maternal cardiovascular risk factors: 1982 Pelotas Birth Cohort
title_full_unstemmed Breastfeeding and maternal cardiovascular risk factors: 1982 Pelotas Birth Cohort
title_short Breastfeeding and maternal cardiovascular risk factors: 1982 Pelotas Birth Cohort
title_sort breastfeeding and maternal cardiovascular risk factors: 1982 pelotas birth cohort
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739402/
https://www.ncbi.nlm.nih.gov/pubmed/31511590
http://dx.doi.org/10.1038/s41598-019-49576-1
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