Cargando…
Bmi1 Suppresses Adipogenesis in the Hematopoietic Stem Cell Niche
Bone marrow stromal cells (BMSCs) that express high levels of stem cell factor (SCF) and CXC chemokine ligand 12 (CXCL12) are one crucial component of the hematopoietic stem cell (HSC) niche. While the secreted factors produced by BMSCs to support HSCs have been well described, little is known regar...
Autores principales: | Hu, Tianyuan, Kitano, Ayumi, Luu, Victor, Dawson, Brian, Hoegenauer, Kevin A., Lee, Brendan H., Nakada, Daisuke |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739622/ https://www.ncbi.nlm.nih.gov/pubmed/31257132 http://dx.doi.org/10.1016/j.stemcr.2019.05.027 |
Ejemplares similares
-
ERα promotes murine hematopoietic regeneration through the Ire1α-mediated unfolded protein response
por: Chapple, Richard H, et al.
Publicado: (2018) -
Nuclear NAD(+) homeostasis governed by NMNAT1 prevents apoptosis of acute myeloid leukemia stem cells
por: Shi, Xiangguo, et al.
Publicado: (2021) -
The histone H3.3 chaperone HIRA restrains erythroid-biased differentiation of adult hematopoietic stem cells
por: Murdaugh, Rebecca L., et al.
Publicado: (2021) -
Bmi1 suppresses protein synthesis and promotes proteostasis in hematopoietic stem cells
por: Burgess, Rebecca J., et al.
Publicado: (2022) -
Highly Efficient Gene Disruption of Murine and Human Hematopoietic Progenitor Cells by CRISPR/Cas9
por: Brunetti, Lorenzo, et al.
Publicado: (2018)