The Ethics of Cerebral Organoid Research: Being Conscious of Consciousness

Recently, the use of three-dimensional neural tissues cultured in vitro and called "cerebral organoids" has advanced recapitulation of neural development and disease modeling studies. Along with such advances, cerebral organoid research, and associated concerns call for the elucidation of...

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Autores principales: Sawai, Tsutomu, Sakaguchi, Hideya, Thomas, Elizabeth, Takahashi, Jun, Fujita, Misao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739740/
https://www.ncbi.nlm.nih.gov/pubmed/31509736
http://dx.doi.org/10.1016/j.stemcr.2019.08.003
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author Sawai, Tsutomu
Sakaguchi, Hideya
Thomas, Elizabeth
Takahashi, Jun
Fujita, Misao
author_facet Sawai, Tsutomu
Sakaguchi, Hideya
Thomas, Elizabeth
Takahashi, Jun
Fujita, Misao
author_sort Sawai, Tsutomu
collection PubMed
description Recently, the use of three-dimensional neural tissues cultured in vitro and called "cerebral organoids" has advanced recapitulation of neural development and disease modeling studies. Along with such advances, cerebral organoid research, and associated concerns call for the elucidation of two points: (1) how cerebral organoid research is currently progressing and the future directions it is likely to take, especially in functional assessment of organoids, and (2) how we should solve ethical issues of possible consciousness in cerebral organoid research. This paper aims first to explore these two issues, and then to present implications and prospects for future cerebral organoid research.
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spelling pubmed-67397402019-09-16 The Ethics of Cerebral Organoid Research: Being Conscious of Consciousness Sawai, Tsutomu Sakaguchi, Hideya Thomas, Elizabeth Takahashi, Jun Fujita, Misao Stem Cell Reports Perspective Recently, the use of three-dimensional neural tissues cultured in vitro and called "cerebral organoids" has advanced recapitulation of neural development and disease modeling studies. Along with such advances, cerebral organoid research, and associated concerns call for the elucidation of two points: (1) how cerebral organoid research is currently progressing and the future directions it is likely to take, especially in functional assessment of organoids, and (2) how we should solve ethical issues of possible consciousness in cerebral organoid research. This paper aims first to explore these two issues, and then to present implications and prospects for future cerebral organoid research. Elsevier 2019-09-10 /pmc/articles/PMC6739740/ /pubmed/31509736 http://dx.doi.org/10.1016/j.stemcr.2019.08.003 Text en © 2019 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Perspective
Sawai, Tsutomu
Sakaguchi, Hideya
Thomas, Elizabeth
Takahashi, Jun
Fujita, Misao
The Ethics of Cerebral Organoid Research: Being Conscious of Consciousness
title The Ethics of Cerebral Organoid Research: Being Conscious of Consciousness
title_full The Ethics of Cerebral Organoid Research: Being Conscious of Consciousness
title_fullStr The Ethics of Cerebral Organoid Research: Being Conscious of Consciousness
title_full_unstemmed The Ethics of Cerebral Organoid Research: Being Conscious of Consciousness
title_short The Ethics of Cerebral Organoid Research: Being Conscious of Consciousness
title_sort ethics of cerebral organoid research: being conscious of consciousness
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739740/
https://www.ncbi.nlm.nih.gov/pubmed/31509736
http://dx.doi.org/10.1016/j.stemcr.2019.08.003
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