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Consistent and correctable bias in metagenomic sequencing experiments

Marker-gene and metagenomic sequencing have profoundly expanded our ability to measure biological communities. But the measurements they provide differ from the truth, often dramatically, because these experiments are biased toward detecting some taxa over others. This experimental bias makes the ta...

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Detalles Bibliográficos
Autores principales: McLaren, Michael R, Willis, Amy D, Callahan, Benjamin J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739870/
https://www.ncbi.nlm.nih.gov/pubmed/31502536
http://dx.doi.org/10.7554/eLife.46923