Inhibition of replication of hepatitis B virus using transcriptional repressors that target the viral DNA

BACKGROUND: Chronic infection with hepatitis B virus (HBV) is a serious global health problem. Persistence of the virus occurs as a result of stability of the replication intermediate comprising covalently closed circular DNA (cccDNA). Development of drugs that are capable of disabling this cccDNA i...

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Detalles Bibliográficos
Autores principales: Bloom, Kristie, Kaldine, Haajira, Cathomen, Toni, Mussolino, Claudio, Ely, Abdullah, Arbuthnot, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739920/
https://www.ncbi.nlm.nih.gov/pubmed/31510934
http://dx.doi.org/10.1186/s12879-019-4436-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739920/
https://www.ncbi.nlm.nih.gov/pubmed/31510934
http://dx.doi.org/10.1186/s12879-019-4436-y

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