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Claudin-12 is not required for blood–brain barrier tight junction function

BACKGROUND: The blood–brain barrier (BBB) ensures central nervous system (CNS) homeostasis by strictly controlling the passage of molecules and solutes from the bloodstream into the CNS. Complex and continuous tight junctions (TJs) between brain endothelial cells block uncontrolled paracellular diff...

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Detalles Bibliográficos
Autores principales: Castro Dias, Mariana, Coisne, Caroline, Baden, Pascale, Enzmann, Gaby, Garrett, Lillian, Becker, Lore, Hölter, Sabine M., Hrabě de Angelis, Martin, Deutsch, Urban, Engelhardt, Britta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739961/
https://www.ncbi.nlm.nih.gov/pubmed/31511021
http://dx.doi.org/10.1186/s12987-019-0150-9