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CD73 complexes with emmprin to regulate MMP-2 production from co-cultured sarcoma cells and fibroblasts

BACKGROUND: Interaction between cancer cells and fibroblasts mediated by extracellular matrix metalloproteinase inducer (emmprin, CD147) is important in the invasion and proliferation of cancer cells. However, the exact mechanism of emmprin mediated stimulation of matrix metalloprotease-2 (MMP-2) pr...

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Detalles Bibliográficos
Autores principales: Aoki, M., Koga, K., Miyazaki, M., Hamasaki, M., Koshikawa, N., Oyama, M., Kozuka-Hata, H., Seiki, M., Toole, B. P., Nabeshima, K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739984/
https://www.ncbi.nlm.nih.gov/pubmed/31510956
http://dx.doi.org/10.1186/s12885-019-6127-x