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CD73 complexes with emmprin to regulate MMP-2 production from co-cultured sarcoma cells and fibroblasts
BACKGROUND: Interaction between cancer cells and fibroblasts mediated by extracellular matrix metalloproteinase inducer (emmprin, CD147) is important in the invasion and proliferation of cancer cells. However, the exact mechanism of emmprin mediated stimulation of matrix metalloprotease-2 (MMP-2) pr...
Autores principales: | Aoki, M., Koga, K., Miyazaki, M., Hamasaki, M., Koshikawa, N., Oyama, M., Kozuka-Hata, H., Seiki, M., Toole, B. P., Nabeshima, K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739984/ https://www.ncbi.nlm.nih.gov/pubmed/31510956 http://dx.doi.org/10.1186/s12885-019-6127-x |
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