Degradation of integral membrane proteins modified with the photosensitive degron module requires the cytosolic endoplasmic reticulum–associated degradation pathway

Protein quality mechanisms are fundamental for proteostasis of eukaryotic cells. Endoplasmic reticulum–associated degradation (ERAD) is a well-studied pathway that ensures quality control of secretory and endoplasmic reticulum (ER)–resident proteins. Different branches of ERAD are involved in degrad...

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Detalles Bibliográficos
Autores principales: Scheffer, Johannes, Hasenjäger, Sophia, Taxis, Christof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6740197/
https://www.ncbi.nlm.nih.gov/pubmed/31411939
http://dx.doi.org/10.1091/mbc.E18-12-0754

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