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Activation of the Ca(2+) sensing receptor and the PKC/WNK4 downstream signaling cascade induces incorporation of ZO-2 to tight junctions and its separation from 14-3-3

Zonula occludens-2 (ZO-2) is a tight junction (TJ) cytoplasmic protein, whose localization varies according to cell density and Ca(2+) in the media. In cells cultured in low calcium (LC), ZO-2 displays a diffuse cytoplasmic distribution, but activation of the Ca(2+) sensing receptor (CaSR) with Gd(3...

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Detalles Bibliográficos
Autores principales: Amaya, Elida, Alarcón, Lourdes, Martín-Tapia, Dolores, Cuellar-Pérez, Francisco, Cano-Cortina, Misael, Ortega-Olvera, Jose Mario, Cisneros, Bulmaro, Rodriguez, Alexis J., Gamba, Gerardo, González-Mariscal, Lorenza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6741067/
https://www.ncbi.nlm.nih.gov/pubmed/31318316
http://dx.doi.org/10.1091/mbc.E18-09-0591

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