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ESBL‐production in Escherichia coli and Klebsiella pneumoniae isolates from Nigeria

The worldwide increase in infections caused by extended‐spectrum beta‐lactamase‐ (ESBL) and AmpC‐producing Enterobacteriaceae (ESBL‐E) is a concern. Surveillance is extensive in Europe, North America, and Asia. Yet, there is no summarizing surveillance in Africa. This study aimed to perform a prelim...

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Autores principales: Hertz, Frederik B., Jansåker, Fillip, Okon, Kenneth O., Abdulmumin, Ibrahim S., Onah, Joseph O., Ladan, Joshua, Knudsen, Jenny D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6741120/
https://www.ncbi.nlm.nih.gov/pubmed/30801967
http://dx.doi.org/10.1002/mbo3.816
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author Hertz, Frederik B.
Jansåker, Fillip
Okon, Kenneth O.
Abdulmumin, Ibrahim S.
Onah, Joseph O.
Ladan, Joshua
Knudsen, Jenny D.
author_facet Hertz, Frederik B.
Jansåker, Fillip
Okon, Kenneth O.
Abdulmumin, Ibrahim S.
Onah, Joseph O.
Ladan, Joshua
Knudsen, Jenny D.
author_sort Hertz, Frederik B.
collection PubMed
description The worldwide increase in infections caused by extended‐spectrum beta‐lactamase‐ (ESBL) and AmpC‐producing Enterobacteriaceae (ESBL‐E) is a concern. Surveillance is extensive in Europe, North America, and Asia. Yet, there is no summarizing surveillance in Africa. This study aimed to perform a preliminary investigation on the prevalence of ESBL‐E in the northeastern part of Nigeria. However, of the 60 samples collected, we were able to culture 15 Escherichia coli and 7 Klebsiella spp. only. In the collection of clinical hospital samples, we found eight of 15 E. coli isolates to be ESBL (53%) and two out of seven Klebsiella spp. to be ESBL/AmpC (29%). Due to the limitations of this study, our findings cannot take a broad view on the prevalence of ESBL‐E, in Nigeria and other parts of Africa. Yet, to know which genes encode ESBL in Nigeria, and to know exact prevalence of every ESBL gene would be of importance.
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spelling pubmed-67411202019-09-13 ESBL‐production in Escherichia coli and Klebsiella pneumoniae isolates from Nigeria Hertz, Frederik B. Jansåker, Fillip Okon, Kenneth O. Abdulmumin, Ibrahim S. Onah, Joseph O. Ladan, Joshua Knudsen, Jenny D. Microbiologyopen Commentaries The worldwide increase in infections caused by extended‐spectrum beta‐lactamase‐ (ESBL) and AmpC‐producing Enterobacteriaceae (ESBL‐E) is a concern. Surveillance is extensive in Europe, North America, and Asia. Yet, there is no summarizing surveillance in Africa. This study aimed to perform a preliminary investigation on the prevalence of ESBL‐E in the northeastern part of Nigeria. However, of the 60 samples collected, we were able to culture 15 Escherichia coli and 7 Klebsiella spp. only. In the collection of clinical hospital samples, we found eight of 15 E. coli isolates to be ESBL (53%) and two out of seven Klebsiella spp. to be ESBL/AmpC (29%). Due to the limitations of this study, our findings cannot take a broad view on the prevalence of ESBL‐E, in Nigeria and other parts of Africa. Yet, to know which genes encode ESBL in Nigeria, and to know exact prevalence of every ESBL gene would be of importance. John Wiley and Sons Inc. 2019-02-22 /pmc/articles/PMC6741120/ /pubmed/30801967 http://dx.doi.org/10.1002/mbo3.816 Text en © 2019 The Authors. MicrobiologyOpen published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Commentaries
Hertz, Frederik B.
Jansåker, Fillip
Okon, Kenneth O.
Abdulmumin, Ibrahim S.
Onah, Joseph O.
Ladan, Joshua
Knudsen, Jenny D.
ESBL‐production in Escherichia coli and Klebsiella pneumoniae isolates from Nigeria
title ESBL‐production in Escherichia coli and Klebsiella pneumoniae isolates from Nigeria
title_full ESBL‐production in Escherichia coli and Klebsiella pneumoniae isolates from Nigeria
title_fullStr ESBL‐production in Escherichia coli and Klebsiella pneumoniae isolates from Nigeria
title_full_unstemmed ESBL‐production in Escherichia coli and Klebsiella pneumoniae isolates from Nigeria
title_short ESBL‐production in Escherichia coli and Klebsiella pneumoniae isolates from Nigeria
title_sort esbl‐production in escherichia coli and klebsiella pneumoniae isolates from nigeria
topic Commentaries
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6741120/
https://www.ncbi.nlm.nih.gov/pubmed/30801967
http://dx.doi.org/10.1002/mbo3.816
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