Mechanical properties of tubulin intra- and inter-dimer interfaces and their implications for microtubule dynamic instability

Thirteen tubulin protofilaments, made of αβ-tubulin heterodimers, interact laterally to produce cytoskeletal microtubules. Microtubules exhibit the striking property of dynamic instability, manifested in their intermittent growth and shrinkage at both ends. This behavior is key to many cellular proc...

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Detalles Bibliográficos
Autores principales: Fedorov, Vladimir A., Orekhov, Philipp S., Kholina, Ekaterina G., Zhmurov, Artem A., Ataullakhanov, Fazoil I., Kovalenko, Ilya B., Gudimchuk, Nikita B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742422/
https://www.ncbi.nlm.nih.gov/pubmed/31469822
http://dx.doi.org/10.1371/journal.pcbi.1007327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742422/
https://www.ncbi.nlm.nih.gov/pubmed/31469822
http://dx.doi.org/10.1371/journal.pcbi.1007327

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