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Mechanical properties of tubulin intra- and inter-dimer interfaces and their implications for microtubule dynamic instability
Thirteen tubulin protofilaments, made of αβ-tubulin heterodimers, interact laterally to produce cytoskeletal microtubules. Microtubules exhibit the striking property of dynamic instability, manifested in their intermittent growth and shrinkage at both ends. This behavior is key to many cellular proc...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742422/ https://www.ncbi.nlm.nih.gov/pubmed/31469822 http://dx.doi.org/10.1371/journal.pcbi.1007327 |