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Extensive ribosome and RF2 rearrangements during translation termination

Protein synthesis ends when a ribosome reaches an mRNA stop codon. Release factors (RFs) decode the stop codon, hydrolyze peptidyl-tRNA to release the nascent protein, and then dissociate to allow ribosome recycling. To visualize termination by RF2, we resolved a cryo-EM ensemble of E. coli 70S•RF2...

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Detalles Bibliográficos
Autores principales:	Svidritskiy, Egor, Demo, Gabriel, Loveland, Anna B, Xu, Chen, Korostelev, Andrei A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2019
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742477/ https://www.ncbi.nlm.nih.gov/pubmed/31513010 http://dx.doi.org/10.7554/eLife.46850

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