Structural state recognition facilitates tip tracking of EB1 at growing microtubule ends

The microtubule binding protein EB1 specifically targets the growing ends of microtubules in cells, where EB1 facilitates the interactions of cellular proteins with microtubule plus-ends. Microtubule end targeting of EB1 has been attributed to high-affinity binding of EB1 to GTP-tubulin that is pres...

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Detalles Bibliográficos
Autores principales: Reid, Taylor A, Coombes, Courtney, Mukherjee, Soumya, Goldblum, Rebecca R, White, Kyle, Parmar, Sneha, McClellan, Mark, Zanic, Marija, Courtemanche, Naomi, Gardner, Melissa K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742484/
https://www.ncbi.nlm.nih.gov/pubmed/31478831
http://dx.doi.org/10.7554/eLife.48117

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