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ΔNp63α suppresses cells invasion by downregulating PKCγ/Rac1 signaling through miR-320a

ΔNp63α, a member of the p53 family of transcription factors, is overexpressed in a number of cancers and plays a role in proliferation, differentiation, migration, and invasion. ΔNp63α has been shown to regulate several microRNAs that are involved in development and cancer. We identified miRNA miR-3...

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Detalles Bibliográficos
Autores principales: Aljagthmi, Amjad A., Hill, Natasha T., Cooke, Mariana, Kazanietz, Marcelo G., Abba, Martín C., Long, Weiwen, Kadakia, Madhavi P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742631/
https://www.ncbi.nlm.nih.gov/pubmed/31515469
http://dx.doi.org/10.1038/s41419-019-1921-6