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The EYA3 tyrosine phosphatase activity promotes pulmonary vascular remodeling in pulmonary arterial hypertension

In pulmonary hypertension vascular remodeling leads to narrowing of distal pulmonary arterioles and increased pulmonary vascular resistance. Vascular remodeling is promoted by the survival and proliferation of pulmonary arterial vascular cells in a DNA-damaging, hostile microenvironment. Here we rep...

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Detalles Bibliográficos
Autores principales: Wang, Yuhua, Pandey, Ram Naresh, York, Allen J., Mallela, Jaya, Nichols, William C., Hu, Yueh-Chiang, Molkentin, Jeffery D., Wikenheiser-Brokamp, Kathryn A., Hegde, Rashmi S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742632/
https://www.ncbi.nlm.nih.gov/pubmed/31515519
http://dx.doi.org/10.1038/s41467-019-12226-1