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The EYA3 tyrosine phosphatase activity promotes pulmonary vascular remodeling in pulmonary arterial hypertension
In pulmonary hypertension vascular remodeling leads to narrowing of distal pulmonary arterioles and increased pulmonary vascular resistance. Vascular remodeling is promoted by the survival and proliferation of pulmonary arterial vascular cells in a DNA-damaging, hostile microenvironment. Here we rep...
Autores principales: | Wang, Yuhua, Pandey, Ram Naresh, York, Allen J., Mallela, Jaya, Nichols, William C., Hu, Yueh-Chiang, Molkentin, Jeffery D., Wikenheiser-Brokamp, Kathryn A., Hegde, Rashmi S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742632/ https://www.ncbi.nlm.nih.gov/pubmed/31515519 http://dx.doi.org/10.1038/s41467-019-12226-1 |
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